HMOX1 anticorps (AA 12-25)

N° du produit ABIN305794

Cet anticorps Lapin Polyclonal détecte spécifiquement HMOX1 dans WB, IHC et IHC (fro). Il présente une réactivité envers Humain, Rat, Souris, Porc, Boeuf (Vache), Chien, Singe, Hamster, Roussette (Chauve-souris) et Xenopus laevis.

Aperçu rapide pour HMOX1 anticorps (AA 12-25) (ABIN305794)

Antigène: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Reactivité: Humain, Rat, Souris, Porc, Boeuf (Vache), Chien, Singe, Hamster, Roussette (Chauve-souris), Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMOX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-HMOX1 anticorps

Épitope: AA 12-25

Specificité: Recognizes human heme oxygenase-1 (HO-1), a 288 amino acid enzyme with a crucial role in heme catabolism, cleaving the heme ring to form biliverdin which is further processed to form bilirubin by a reductase enzyme. HO-1 acitivity is highest in the spleen where it is involved in the processing of senescent erythrocytes. HO-1expression can be increased during cellular stress, including heat shock. Baseline levels of expression are high in certain tissues, including spleen and liver. Enriched enzyme preparations are recommended for experimental analysis.

Aucune reactivité croisée: Chien

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Pig, Opossum, Platypus, Xenopus (100%) Turkey, Chicken, Lizard (93%).

Purification: Purified IgG

Immunogène: Synthetic peptide with the amino acid sequence DLSEALKEATKEVHC corresponding to residues 12-25 of human heme oxygenase 1. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Pig, Opossum, Platypus, Xenopus (100%), Turkey, Chicken, Lizard (93%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: IHC, IHC-Fr, WB (1:500 - 1:2000)

Usage: Western Blot: Heme oxygenase 1 demonstrates a single band of approximately 32kD. Immunohistology: LS-C11351 reacts with human spleen, kidney and airway biopsies, as well as pig arteries.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Short term: -20°C
Long term: -20°C.

Détails sur HMOX1

Antigène: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Autre désignation: HMOX1 / HO-1

Sujet: Name/Gene ID: HMOX1

Synonyms: HMOX1, BK286B10, HO-1, HSP32, Heat shock protein, 32-kD, Heme oxygenase (decycling) 1, Heme oxygenase 1, HO1

ID gène: 3162

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome